Evaluating TRYPTYR as a Novel Therapy for Dry Eye in Patients With Sjögren's Syndrome
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY
This study will evaluate the effect of TRYPTYR in patients with Sjögren's syndrome-related dry eye disease. The goal is to determine whether TRYPTYR can improve symptoms and signs of dry eye in this specific patient population.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
⁃ Subjects must fulfill the following conditions to qualify for enrollment into the trial
• Adults over 18 years old with a diagnosis of dry eye disease (DED) secondary to Sjögren's Syndrome within the past 2 years.
• History of using or desiring artificial tears for DED symptoms within the past 2 months.
• Unanesthetized Schirmer's Test (UA ST) score ≥1 and \< 10 mm/5 min and baseline total Corneal Fluorescein Staining (tCFS) score ≥2 and ≤ 15 (National Eye Institute, NEI, grading scale).
Locations
United States
Florida
Center For Sight
RECRUITING
Venice
Contact Information
Primary
Gina Thomas
gina.thomas@useye.com
9412634784
Time Frame
Start Date: 2025-12-02
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 35
Treatments
Experimental: Study eye
The study eye is the eye with the lower pre-drop unanesthetized Schirmer score performed at the baseline visit.
Related Therapeutic Areas
Sponsors
Leads: Center For Sight